The fixtures you must watch this weekend, including massive derbies in English football and a clash between two Serie A superpowers.
Here are our five must-watch games.
5️⃣ spicy fixtures you must watch this weekend 🌶
Atletico Madrid vs Villarreal
Atletico Madrid have endured a nightmare start to the campaign with the pressure on Diego Simeone for, arguably, the first time in his long tenure. Three games without a win have ramped up the scrutiny, with Simeone admitting performances have not been good enough. Atletico need points, but face a Villarreal side who have started the season strongly.
Spice rating: Mild 🌶
Read – In search of your next great football read? Look no further
Southampton vs Portsmouth
Southampton host Portsmouth on Sunday in the first league South Coast derby in over a decade.
The Saints have had a mixed start to the Championship campaign after top-flight relegation last season, with Portsmouth two points and five places above them in the table. Expect fireworks when the arch-rivals collide in a hugely anticipated South Coast contest.
40 – Southampton and Portsmouth will face off for the 40th time on Sunday and first time since a 4-0 victory for the Saints in the League Cup in September 2019. Meanwhile, Pompey will be looking to win an away league game against their rivals for the first time since January… pic.twitter.com/aDVn3HCSyA
— OptaJoe (@OptaJoe) September 12, 2025
Spice rating: Medium 🌶🌶
West Ham vs Tottenham Hotspur
West Ham recovered from a poor start to beat Nottingham Forest before the international break, a welcome win as the pressure mounted on Graham Potter. The Irons will hope to build on that success when fierce rivals Tottenham Hotspur arrive at the London Stadium this weekend. Thomas Frank’s side opened the season with consecutive wins, but suffered a setback after losing to Bournemouth before the break.
Mohammed Kudus makes his first return to West Ham and is unlikely to receive a warm welcome…
Meanwhile, at a London pub, West Ham fans made this sign for Mohammed Kudus with a snake that says “Judus” after he joined Tottenham. pic.twitter.com/dxQrh3KU7u
— Football Zone (@footballzone525) August 16, 2025
Spice rating: Hot 🌶🌶🌶
Juventus vs Inter
The Serie A season’s first Derby d’Italia is perfectly poised, as Juventus welcome Inter Milan to Turin.
Igor Tudor’s side have won consecutive games without conceding a goal, increasing optimism around the Old Lady. Inter’s treble dream fell apart last season, while the Nerazzurri are dealing with the departure of head coach Simeone Inzaghi.
Cristian Chivu has taken the reins but remains inexperienced at this level. After a shock setback at home to Udinese before the break, Inter will not want to lose further ground.
Spice rating: Fire 🌶 🌶 🌶 🌶
Manchester City vs Manchester United
Manchester will pause on Sunday afternoon for a derby clash at the Etihad. Neither side has started the season as expected, ahead of the 197th meeting between the teams.
City will start as strong favourites despite losing their last two, with Erling Haaland entering the game after scoring five times for Norway against Moldova earlier this week.
International break: over.
Club football and a Manchester derby to look forward to this weekend ⏳ pic.twitter.com/XFAxAh9APP
— B/R Football (@brfootball) September 10, 2025
Manchester United are yet to get to grips with Ruben Amorim’s system, though summer signings Bryan Mbeumo and Benjamin Sesko offer threat on the counter.